At a recent shoot I found myself shooting with lower levels of natural light, and wanting to retain the flexibility of hand holding with a decent depth of field.
For this I utilised Ilford Delta 3200, a usually very specialist film, and not one often used for smooth skin textures, due to its very noticeable grain and preference for low-light.
Overall the results came out well, but in all cases some additional contras was needed in in the final edit.